Dissecting Vulvodynia by high resolution omics

Women's health Genomics Lab focuses on molecular mechanisms regulating gene expression in health and disease. We are particularly interested in the transcriptional regulation by transcription factors, which crucially control cell differentiation and plasticity.

Impact of Vulvodynia on Women's Lives

Vulvodynia can significantly impair not only woman's sexual life but also everyday activities like sitting, wearing tight clothing, sports, and even walking. Diagnosis is challenging as it's a "diagnosis of exclusion," made when other diseases are ruled out. Despite its prevalence, vulvodynia is often overlooked due to the lack of specific markers. For these reasons we are conducting transcriptomic analyses on patients to identify specific disease biomarkers to ease the diagnosis of this multifactorial disease.

Empowering Women's Health Research

Research fundings

In 2022, in order to secure funding for this research project, we collaborated with the "Comitato Vulvodinia e Neuropatia del Pudendo," to organize a crowdfunding campaign called "doppiaVproject." This campaign successfully raised over 20,000 euros. Furthermore, we have recently received funding from the Ministry of Research (MUR) and from the Fondazione CRT (Cassa di Risparmio di Torino) to further pursue our objectives (PRIN 2022).

Empowering Precision Medicine for VPD

Explore our efforts to tackle Vulvar Extramammary Paget Disease (VPD), a challenging form of epithelial cancer. Through personalized therapeutic strategies, we endeavor to minimize invasive surgical interventions and optimize patient outcomes.

Collaborative Initiatives for Women's Health

We foster collaboration with esteemed partners like the "Comitato Vulvodinia e Neuropatia del Pudendo" and the AIRC- Fondazione AIRC per la Ricerca sul Cancro, amplifying our impact in advancing women's health research.

Join us on a journey to understand and combat vulvodynia, a debilitating condition affecting countless women worldwide. Through transcriptomic analyses, we aim to uncover specific biomarkers, revolutionizing diagnosis and treatment approaches.

See our publications